The Journal of pediatrics
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The Journal of pediatrics · Sep 2013
Bicycle helmet laws are associated with a lower fatality rate from bicycle-motor vehicle collisions.
To assess the association between bicycle helmet legislation and bicycle-related deaths sustained by children involved in bicycle-motor vehicle collisions. ⋯ Bicycle helmet safety laws are associated with a lower incidence of fatalities in child cyclists involved in bicycle-motor vehicle collisions.
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The Journal of pediatrics · Sep 2013
Histological characteristics of the fetal inflammatory response associated with neurodevelopmental impairment and death in extremely preterm infants.
To test the hypothesis that increasing severity of the fetal inflammatory response (FIR) would have a dose-dependent relationship with severe neurodevelopmental impairment or death in extremely preterm infants. ⋯ Severe FIR, characterized by subacute necrotizing funisitis and severe chorionic plate vasculitis with thrombosis, is associated with severe neurodevelopmental impairment/death in preterm infants.
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The Journal of pediatrics · Sep 2013
Review Meta AnalysisDoes the use of antipyretics in children who have acute infections prolong febrile illness? A systematic review and meta-analysis.
To review the literature and test the hypothesis that the use of antipyretic drugs in children with acute infections slows recovery. ⋯ There is no evidence from these studies that the use of antipyretics slows the resolution of fever in children.
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The Journal of pediatrics · Sep 2013
Multicenter StudyImpact of gender on sepsis mortality and severity of illness for prepubertal and postpubertal children.
To investigate differences in sepsis mortality between prepubertal and postpubertal males and females. ⋯ Sepsis mortality is similar in prepubertal males and females. However, postpubertal males have a higher sepsis mortality than postpubertal females, likely related to their greater severity of illness on PICU admission. These outcome differences in postpubertal children may reflect a hormonal influence on the response to infection or differences in underlying comorbidities, source of infection, or behavior.
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The Journal of pediatrics · Sep 2013
Trends in Clostridium difficile infection and risk factors for hospital acquisition of Clostridium difficile among children with cancer.
To study the trend of Clostridium difficile infection (CDI) and risk factors for hospital acquired CDI (HA-CDI) among children with cancer. ⋯ Despite an apparent decrease in CDI incidence from 2006-2010, HA-CDI remains prevalent and morbid among children with cancer. Recent exposure to chemotherapy, proton pump inhibitor, and certain antibiotics were independent risk factors for HA-CDI.