The Journal of pediatrics
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The Journal of pediatrics · Mar 2008
Comparative StudyApparent life-threatening events and sudden infant death syndrome: comparison of risk factors.
To compare the risk factors of 153 cases of apparent life-threatening event (ALTE) enrolled in the multicenter Collaborative Home Infant Monitoring Evaluation (CHIME) from 1994 to 1998 with the published risk factors for sudden infant death syndrome (SIDS). ⋯ Although a number of risk factors for ALTE are similar to those for SIDS, the differences warrant a separate focus on ALTE beyond that on SIDS.
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The Journal of pediatrics · Mar 2008
Sensitivity of the bacterial meningitis score in 889 children with bacterial meningitis.
To validate sensitivity of the bacterial meningitis score (BMS) in a large population of children with bacterial meningitis (BM). ⋯ The sensitivity of the BMS to detect disease was very high, but a few cases of BM were missed. Further refinements of the BMS may be warranted to lower the false-negative rate.
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The Journal of pediatrics · Mar 2008
Medication use in the neonatal intensive care unit: current patterns and off-label use of parenteral medications.
To study the current patterns of medication use, assess the extent of off-label parenteral medication use, and evaluate evidence for efficacy and safety of parenteral medications used off-label in neonates. ⋯ Critically ill neonates are exposed to numerous medications, a significant proportion of which are not yet FDA-approved for use in this vulnerable group of patients.
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The Journal of pediatrics · Feb 2008
Risk factors in preventable adverse drug events in pediatric outpatients.
To determine whether there are racial/ethnic, socioeconomic, parental linguistic, or parental educational disparities in children who experienced an adverse drug event (ADE) in the ambulatory setting. ⋯ Children with multiple prescriptions are at increased risk of having a preventable ADE. Further attention should be directed toward improved communication among healthcare providers and patients.
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The Journal of pediatrics · Feb 2008
Vaso-occlusive episodes in older children with sickle cell disease: emergency department management and pain assessment.
To describe emergency department (ED) management of older children with sickle cell disease (SCD) experiencing a vaso-occlusive episode (VOE) and factors associated with disposition and ED return. ⋯ Suboptimal pain relief after 1 dose of IV morphine was associated with admission from the ED. Further investigation of pain relief, using validated pain assessment scales, as an outcome in VOE management is warranted.