The Journal of pediatrics
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The Journal of pediatrics · Sep 2005
Variables associated with the early failure of nasal CPAP in very low birth weight infants.
To identify risk factors and neonatal outcomes associated with the early failure of "bubble" nasal continuous positive airway pressure (CPAP) in very low birth weight (VLBW) infants with respiratory distress syndrome (RDS). ⋯ Although several variables available near birth were strongly associated with early CPAP failure, they proved weak predictors of failure. A prospective controlled trial is needed to determine if extremely premature spontaneously breathing infants are better served by initial management with CPAP or mechanical ventilation.
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The Journal of pediatrics · Aug 2005
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialComparative efficacy and safety of low-dose fluticasone propionate and montelukast in children with persistent asthma.
To evaluate efficacy, safety, health outcomes, and cost-effectiveness of fluticasone propionate (FP) versus montelukast (MON) in 342 children (6 to 12 years of age) with persistent asthma. ⋯ FP was significantly more effective than MON in improving pulmonary function, asthma symptoms, and rescue albuterol use. Both therapies had similar safety profiles. Parent- and physician-reported satisfaction ratings were higher with FP treatment, and asthma-related costs were lower.