The Journal of pediatrics
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The Journal of pediatrics · Jan 2004
Outcomes from an interprovincial program of newborn open heart surgery.
To determine 18-month neurodevelopmental outcome of survivors of complex open heart surgery at
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The Journal of pediatrics · Jan 2004
Case ReportsPosthemorrhagic unilateral hydrocephalus: fenestration of septum pellucidum as an alternative to shunt implantation.
Unilateral hydrocephalus caused by occlusion of the foramen of Monro is rare. We report two cases in neonates caused by prenatal hemorrhage, their radiographic findings, and surgical treatment. With posthemorrhagic progressive unilateral hydrocephalus, early intervention with fenestration of septum pellucidum should be considered.
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The Journal of pediatrics · Dec 2003
ReviewGlobal reduction of Hib disease: what are the next steps? Proceedings of the meeting Scottsdale, Arizona, September 22-25, 2002.
On September 22 to 25, 2002, a group of infectious disease specialists, public health officials, and vaccine experts from 33 countries gathered in Scottsdale, Arizona, to discuss the epidemiology and control of disease caused by Haemophilus influenzae type b (Hib) in the era of Hib conjugate vaccines. This supplement is a synthesis of the major themes and key lessons identified at the meeting. The objectives of the conference were to review the 10-year experience with Hib conjugate vaccines, discuss strategies to reduce Hib disease rates to lowest possible levels in industrialized countries, review impediments to the introduction of Hib vaccine in developing countries, and discuss strategies for disseminating lessons learned from countries using to those not using Hib conjugate vaccines. ⋯ In countries that are not using Hib conjugate vaccine, information on the local burden of Hib disease will be essential for leaders considering vaccine introduction. Where disease burden is high, a multifaceted approach is urgently needed to evaluate and overcome barriers to vaccine introduction. In areas where Hib disease burden is not well characterized, additional work will be needed to understand the epidemiology of Hib disease and to communicate the value of Hib conjugate vaccine.
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The Journal of pediatrics · Dec 2003
Clinical Trial Controlled Clinical TrialBenefit and risk of heparin for maintaining peripheral venous catheters in neonates: a placebo-controlled trial.
Heparin addition to infusion fluids is used to prolong catheter patency in newborns. Heparin may also induce adverse effects such as bleeding complications and immune-mediated heparin-induced thrombocytopenia (HIT). One objective was peripheral venous catheter patency with heparinization of continuous infusions (0.5 IU/mL). Secondary objectives were incidences of bleeding, clinically manifest HIT, HIT antibodies, and catheter-related complications. ⋯ Balancing the benefits against the risks of heparin addition and the rare complication of HIT, we will not use 0.5 IU/mL heparin addition to parenteral fluids.
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The Journal of pediatrics · Nov 2003
Fetal rhabdomyoma: prenatal diagnosis, clinical outcome, and incidence of associated tuberous sclerosis complex.
We reviewed our institution's experience with fetal cardiac rhabdomyoma to document the clinical outcome and incidence of associated tuberous sclerosis complex (TSC) and compared our findings with those of patients diagnosed with cardiac rhabdomyoma after birth. ⋯ Cardiac rhabdomyomas are benign from the cardiovascular standpoint in most affected fetuses. As observed in postnatally diagnosed cardiac rhabdomyoma, TSC is diagnosed in most cases of fetal cardiac rhabdomyoma.