The Journal of pediatrics
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The Journal of pediatrics · Dec 1981
Randomized Controlled Trial Clinical TrialThe efficacy of caffeine in the treatment of recurrent idiopathic apnea in premature infants.
This prospective controlled study was aimed at evaluating the efficacy of caffeine in treating recurrent idiopathic apnea in the premature infant. Eighteen preterm infants (29 to 35 weeks' gestation) were studied. ⋯ No treatment of apnea other than caffeine was required in group I, whereas six neonates in group II had such severe and frequent apneic episodes for more than 48 hours that withholding additional treatment was believed to be unethical. No undesirable side effects of caffeine treatment were observed.
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The Journal of pediatrics · Oct 1981
Physiologic responses to prolonged and slow-rise inflation in the resuscitation of the asphyxiated newborn infant.
Measurements of thoracic volume, inflation pressure, and intrathoracic pressure have been recorded at the resuscitation of nine newborn babies. The initial inflation pressure was maintained for approximately five seconds which produced a twofold increase in inflation volume compared to standard resuscitation techniques and always led to formation of an FRC. When the inflation pressure was increased slowly over three to five seconds, the apparent opening pressure which occurred universally in square wave inflation was rarely seen.