The Journal of pediatrics
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The Journal of pediatrics · Mar 1976
Transfusion therapy for cerebrovascular abnormalities in sickle cell disease.
Cerebral angiograms were performed in patients with sickle cell disease and symptoms of stroke to evaluate transfusion therapy for cerebrovascular accidents. Three patients who were transfused repeatedly for one year to maintain less than 30% hemoglobin S were compared to two patients who were not transfused. ⋯ The two children who were not transfused showed progressive vascular disease. For all arteriograms, the patients were prepared by transfusion with normal red cells and careful hydration.
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The Journal of pediatrics · Dec 1975
Clinical Trial Controlled Clinical TrialImmunologic and virologic studies in the postpericardiotomy syndrome.
A prospective, triple-blind study was undertaken to determine whether antiheart antibody or a rise in titer to a virus occurred in patients after intrapericardial surgery and, if so, whether either was related to clinical evidence of the postpericardiotomy syndrome. In 257 patients, AHA in high titer appeared in 62 (24%), all of whom had the syndrome. ⋯ In 137 subjects, a rise in titer to one or more viral agents occurred in 21 of 31 (68%) of those with AHA and PPS. This study suggests that an immunologic response and viral illness are related to PPS.
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The Journal of pediatrics · Aug 1975
Studies of adoptees from psychiatrically disturbed biologic parents. II. Temperament, hyperactive, antisocial, and developmental variables.
Temperament, hyperactivity, antisocial behavior, and developmental milestones were assessed in two groups of adoptees by interviewing the adoptive parents. One group, the "experimental," was born of psychiatrically disturbed biologic parents (N = 59). The second group, the "control," had psychiatrically "normal" parents (N = 54). ⋯ Male "experimental" adoptees had excess number of temperament traits characteristic of the "difficult" child, as well as an excess of antisocial behaviors when contrasted with male control subjects. No differences between control and experimental females were found for these variables. Hyperactive behavior in the adoptees of each sex was associated more with antisocial parentage than in those of "normal" parentage.