The Journal of pediatrics
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The Journal of pediatrics · Feb 1975
Experimental salicylate intoxication in young baboons. A preliminary report.
Salicylate intoxication has been investigated in young baboons. The results of these studies are similar to these previously obtained in man. ⋯ The CSF concentration of salicylate seems to be of major physiologic importance in this condition. Moreover, the serum concentration of free salicylate correlates more closely with the CSF concentration of salicylate than does the total serum concentration of salicylate.
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The Journal of pediatrics · Oct 1974
Comparative Study Clinical TrialGreater frequency of viral respiratory infections in asthmatic children as compared with their nonasthmatic siblings.
A longitudinal clincal and microbiologic surveillance was conducted from October to May, 1971-72, on 16 children with infectious asthma and 15 of their nonasthmatic siblings. Asthmatic children experienced a significantly greater frequency of viral respiratory infections than did nonasthmatic ones (5.1 vs. 3.8 per subject). This increased incidence appeared to be largely the result of a greater number of rhinovirus infections. While respiratory infections of identical etiology that occurred concurrently in an asthmatic and his sibling were equivalent in severity, illnesses were longer (but not significantly so) in asthmatic children.