The Journal of pediatrics
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The Journal of pediatrics · Apr 2015
Plasma and cerebrospinal fluid herpes simplex virus levels at diagnosis and outcome of neonatal infection.
To evaluate the utility of quantitative herpes simplex virus (HSV) polymerase chain reaction (PCR) levels for prognosis and management of neonatal HSV disease. ⋯ Plasma HSV levels correlate with clinical presentation of neonatal HSV disease and mortality, but not neurologic outcome.
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The Journal of pediatrics · Apr 2015
Comparative StudyExhaled carbon dioxide in healthy term infants immediately after birth.
To measure exhaled carbon dioxide (ECO2) in term infants immediately after birth. ⋯ The first breaths for an infant after birth did not contain ECO2. With aeration of the distal gas exchange regions, tidal volume and ECO2 significantly increased. ECO2 can be used to monitor lung aeration immediately after birth.
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The Journal of pediatrics · Apr 2015
Randomized Controlled Trial Multicenter StudyA randomized clinical trial of therapeutic hypothermia mode during transport for neonatal encephalopathy.
To determine if temperature regulation is improved during neonatal transport using a servo-regulated cooling device when compared with standard practice. ⋯ Cooling using a servo-regulated device provides more predictable temperature management during neonatal transport than does usual care for outborn newborns with neonatal encephalopathy.
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The Journal of pediatrics · Apr 2015
Comparative StudyComparison of formulas for calculation of the corrected QT interval in infants and young children.
To compare 4 heart rate correction formulas for calculation of the rate corrected QT (QTc) interval among infants and young children. ⋯ The Bazett formula calculated the most consistent QTc; 460 ms is the best threshold for prolonged QTc. The study supports continued use of the Bazett formula for infants and children and differs from the use of the Fridericia correction during clinical trials of new medications.