The Journal of pediatrics
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The Journal of pediatrics · Apr 2015
Review Meta AnalysisDiagnosing clinically significant dehydration in children with acute gastroenteritis using noninvasive methods: a meta-analysis.
To determine the most accurate, noninvasive method of assessing dehydration. ⋯ Overall, the clinical scales evaluated provide some improved diagnostic accuracy. However, test characteristics indicate that their ability to identify children both with and without dehydration is suboptimal. Current evidence does not support the routine use of ultrasound or urinalysis to determine dehydration severity.
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The Journal of pediatrics · Apr 2015
Randomized Controlled Trial Multicenter StudyA randomized clinical trial of therapeutic hypothermia mode during transport for neonatal encephalopathy.
To determine if temperature regulation is improved during neonatal transport using a servo-regulated cooling device when compared with standard practice. ⋯ Cooling using a servo-regulated device provides more predictable temperature management during neonatal transport than does usual care for outborn newborns with neonatal encephalopathy.
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The Journal of pediatrics · Apr 2015
Comparative StudyComparison of formulas for calculation of the corrected QT interval in infants and young children.
To compare 4 heart rate correction formulas for calculation of the rate corrected QT (QTc) interval among infants and young children. ⋯ The Bazett formula calculated the most consistent QTc; 460 ms is the best threshold for prolonged QTc. The study supports continued use of the Bazett formula for infants and children and differs from the use of the Fridericia correction during clinical trials of new medications.
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The Journal of pediatrics · Apr 2015
Plasma and cerebrospinal fluid herpes simplex virus levels at diagnosis and outcome of neonatal infection.
To evaluate the utility of quantitative herpes simplex virus (HSV) polymerase chain reaction (PCR) levels for prognosis and management of neonatal HSV disease. ⋯ Plasma HSV levels correlate with clinical presentation of neonatal HSV disease and mortality, but not neurologic outcome.