The American journal of clinical nutrition
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Sucrose has been thought to cause dental caries; sweets and snacks being primarily responsible, together with plaque and their respective interactions. Dietary questionnaires revealed that in 3 to 5 yr olds, protein in black, colored, Indian, and white groups provided 12 to 15% of total intake, fats 10 to 17%, and carbohydrates 69 to 78%. ⋯ This raised several questions regarding current concepts of caries causation. Are genetic, immunological and other dietary factors also responsible for caries levels experienced?
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There is now convincing evidence that vitamin E is a specific erythropoietic factor for nonhuman primates and swine. There is no evidence, however, that vitamin E is normally required as an erythropoietic factor for humans and many species of animals. We propose that the lack of a requirement for vitamin E in erythropoiesis in humans is due to a metabolic adaptation that circumvents the need for the role that the vitamin otherwise would serve. ⋯ These patients respond with reticulocytosis and a limited increase in hemoglobin concentration when vitamin E is given before their metabolic derangement is reversed by correcting their other nutritional deficiencies. Given this information, we may predict that other acquired or congenital abnormalities of metabolism could impair the adaptation that circumvents the role of vitamin E in erythropoiesis. Therefore, vitamin E should be viewed as a potential erythropoietic factor for humans, and it should receive further carefully controlled therapeutic trials in patients with anemia of obscure etiology, particularly in those with erythroid hyperplasia and unexplained ineffective erythropoiesis.
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Comparative Study
Infant feeding practices in rural Meheran, Comilla, Bangladesh.
Since 1930 breast-feeding has declined worldwide. Differences exist in breast-feeding practices between developed and developing countries and between urban and rural people. In order to define the breast-feeding practices in Bangladesh, we studied longitudally 401 rural children and cross-sectionally 193 urban children. ⋯ Mothers should be trained about supplementation of food and the time of supplementation. Breast-feeding is still quite prevalent in the villages of this country. Maternal nutrition and timely supplementation are important for development of children.
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Evidence is accumulating to suggest that selenium (Se) is an essential trace element for man and is reviewed with emphasis on those aspects peculiar to New Zealand. The extremely low Se levels in New Zealand soils results in a low Se content of foods, low dietary intakes, low urinary excretions, and low blood Se concentrations and glutathione peroxidase activities. Of these, plasma Se gives a short-term index of nutritional status while erythrocyte Se and glutathione peroxidase activities give a long-term index. ⋯ It is not yet possible to predict a minimum Se requirement for health but it appears that the intake of New Zealanders might be on the borderline. At present supplementation by the general population is not justified, but may be necessary for certain vulnerable groups such as patients on restricted diets. The most effective means of supplementation for increasing the Se status of New Zealanders is under study.
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Twenty patients who had symptoms that were apparently neurotically functional are reported because they proved to have abnormal red cell transketolase activity. Although in many of the cases the etiology appeared to be associated with heavy consumption of "junk" foods, carbonated or sweet beverages, and candy, this was not so in all of them and the etiology in these cases remains obscure. The symptoms in all 20 patients could be correlated with those well documented in early beriberi and all were clinically improved by the administration of thiamin. ⋯ In 10 patients improved transketolase activity was correlated with clinical well-being. The other 10 patients did not keep their return appointments. Telephone contract revealed that they were asymptomatic.