Journal of cell science
-
Nature Reviews Molecular Cell Biology Nature Publishing Group (2000). ISSN 1471-0072. Monthly First there was Annual Reviews, then came the monthly Elsevier Trends Journals, both of which try to identify hot topics in their chosen fields. ⋯ The magazine has a nice heft to it, and is attractively designed and presented in glossy colour, although the main font is small enough to make reading difficult for your middle-aged reviewer in a particularly heavily overcast and rainy week in London. A first issue is supposed to be a kind of showcase, but if they can keep this up, the editors will surely have a success on their hands and you will probably be obliged to take out a personal subscription (£85), or persuade your library to part with £565. That's slightly cheaper than TiBS and a lot cheaper than Current Opinion in Cell Biology, both of which will have to run faster if they want to stay in the same place.
-
Nature Reviews Molecular Cell Biology Nature Publishing Group (2000). ISSN 1471-0072. Monthly First there was Annual Reviews, then came the monthly Elsevier Trends Journals, both of which try to identify hot topics in their chosen fields. ⋯ The magazine has a nice heft to it, and is attractively designed and presented in glossy colour, although the main font is small enough to make reading difficult for your middle-aged reviewer in a particularly heavily overcast and rainy week in London. A first issue is supposed to be a kind of showcase, but if they can keep this up, the editors will surely have a success on their hands and you will probably be obliged to take out a personal subscription (£85), or persuade your library to part with £565. That's slightly cheaper than TiBS and a lot cheaper than Current Opinion in Cell Biology, both of which will have to run faster if they want to stay in the same place.
-
Journal of cell science · Jan 2000
The invited review ? or, my field, from my standpoint, written by me using only my data and my ideas, and citing only my publications.
Do you feel scientifically isolated? Do you find yourself sitting on the side-line while others take the field by the nose and lead it? Are you unable to publish a model that summarizes your data and ideas because reviewers label it as being too speculative and unsupported? Can't get those experiments published in any regular journal? Do you find that nobody is citing your papers? Haven't published in your field for some time, but want to show that you are still a player? Well, no need to worry. There is a special category of publication for you, 'the invited review', and even specialized journals, the 'review journals', that cater to every part of your neurosis. The major difference between many invited reviews and regular articles in journals ? this journal being an exception ? is that the invited review is generally not critiqued by outside, independent referees. ⋯ Messages for Caveman and other contributors can be left at caveman@biologists.com. Any correspondence may be published in forthcoming issues. Previous Sticky Wickets can be viewed at: www.biologists.com/JCS/caveman/index.html jcs6024
-
Journal of cell science · Oct 1999
VAMP (synaptobrevin) is present in the plasma membrane of nerve terminals.
Synaptic vesicle docking and exocytosis require the specific interaction of synaptic vesicle proteins (such as VAMP/synaptobrevin) with presynaptic plasma membrane proteins (such as syntaxin and SNAP 25). These proteins form a stable, SDS-resistant, multimolecular complex, the SNARE complex. The subcellular distribution of VAMP and syntaxin within Torpedo electric organ nerve endings was studied by immunogoldlabeling of SDS-digested freeze-fracture replicas (Fujimoto, 1995). ⋯ The VAMP to syntaxin stoichiometry in the isolated synaptosomal membrane was estimated by comparison with purified antigens and close to 2, in accordance with morphological data. SDS-resistant SNARE complexes were detected in the isolated presynaptic membrane but absent in purified synaptic vesicles. Taken together, these results show that the presence of VAMP in the plasma membrane of nerve endings cannot result from exocytosis of synaptic vesicles, a process which could, as far as SNAREs are concerned, very much resemble homotypic fusion.