Neuropsych Dis Treat
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Neuropsych Dis Treat · Jan 2013
Salivary alpha-amylase and cortisol responsiveness following electrically stimulated physical stress in bipolar disorder patients.
Bipolar disorder (BP) is often associated with a change in hypothalamus- pituitary-adrenal axis function change due to chronic stress. Salivary α-amylase (sAA) levels increase in response to psychosocial stress and thus function as a marker of sympathoadrenal medullary system activity. However, sAA has been studied less often than salivary cortisol in BP patients. ⋯ These preliminary results suggest that sAA may be a useful biological marker for BP patients.