The Journal of thoracic and cardiovascular surgery
-
J. Thorac. Cardiovasc. Surg. · Jun 2022
Meta AnalysisMachine learning improves mortality risk prediction after cardiac surgery: Systematic review and meta-analysis.
Interest in the usefulness of machine learning (ML) methods for outcomes prediction has continued to increase in recent years. However, the advantage of advanced ML model over traditional logistic regression (LR) remains controversial. We performed a systematic review and meta-analysis of studies comparing the discrimination accuracy between ML models versus LR in predicting operative mortality following cardiac surgery. ⋯ The present findings suggest that when compared with LR, ML models provide better discrimination in mortality prediction after cardiac surgery. However, the magnitude and clinical influence of such an improvement remains uncertain.
-
J. Thorac. Cardiovasc. Surg. · Jun 2022
Pulmonary vein stenosis: Anatomic considerations, surgical management, and outcomes.
The study objective was to evaluate outcomes of pulmonary vein stenosis repair in a large single-center cohort. ⋯ This large single-center surgical pulmonary vein stenosis experience demonstrates encouraging midterm results. A new anatomically focused repair strategy aims to alleviate pulmonary vein angulation to minimize turbulence and shows promising early outcomes. Continued follow-up is required to understand longer-term outcomes for this surgical approach.
-
J. Thorac. Cardiovasc. Surg. · Jun 2022
Multicenter Study Clinical TrialNeoadjuvant pemetrexed plus cisplatin followed by pleurectomy for malignant pleural mesothelioma.
Despite becoming the preferred surgical technique for malignant pleural mesothelioma, pleurectomy/decortication has received few prospective clinical trials. Therefore, the Japan Mesothelioma Interest Group conducted a prospective multi-institutional study to evaluate the feasibility of neoadjuvant chemotherapy followed by pleurectomy/decortication. ⋯ Neoadjuvant chemotherapy followed by pleurectomy/decortication was feasible with acceptable survival and mortality/morbidity. Postoperative pulmonary function was approximately 80% of the preoperative pulmonary function.