Aust Fam Physician
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The antinuclear antibody (ANA) test is widely used as a serological marker of autoimmune disease. Antinuclear antibodies are immunoglobulins or antibodies that bind to one or more antigens expressed within the nucleus of human cells. Used selectively, the ANA test can be a useful laboratory tool to help confirm or exclude the diagnosis of systemic rheumatic disease. However, the relatively high prevalence of ANAs in other inflammatory conditions, as well as healthy individuals, can make a positive result difficult to interpret.
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Fibromyalgia is a common and debilitating condition. The cardinal feature of fibromyalgia is musculoskeletal pain, usually accompanied by other problems, such as fatigue, sleep disturbance and cognitive difficulties. Fibromyalgia commonly coexists with other chronic illnesses and can result in poorer outcomes if untreated. ⋯ The features of fibromyalgia are similar to those of many other chronic illnesses, sometimes resulting in diagnostic confusion. Fibromyalgia can co-exist with other disorders and it is important to consider the possibility of fibromyalgia contributing to symptoms in any chronically ill patient.
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Long-term persistence on warfarin in patients with non-valvular atrial fibrillation is essential to minimise thromboembolic complications, especially ischaemic stroke. This study examines persistence in Australian patients with presumed atrial fibrillation newly prescribed warfarin. ⋯ There is significant discontinuation of warfarin therapy. When due to non-compliance, an opportunity for stroke prevention is being lost.
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This study investigated the prevalence of overweight and obese Indigenous kindergarten children in the Australian Capital Territory. ⋯ The low level of parental concern about obesity suggests that general practitioners should persist with screening for, and managing, overweight and obesity in kindergarten-aged children in similar jurisdictions on a proactive basis.