The Journal of urology
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The Journal of urology · Dec 1995
Randomized Controlled Trial Comparative Study Clinical TrialAlternating mitomycin C and bacillus Calmette-Guerin instillation therapy for carcinoma in situ of the bladder. The Finnbladder Group.
Our aim was to prove if alternating chemotherapeutic and immunotherapeutic instillations improved efficacy and reduced toxicity in patients with carcinoma in situ of the bladder. ⋯ Therapy of carcinoma in situ with alternating mitomycin C and BCG is more effective than mitomycin C alone. Compared to BCG monotherapy only few side effects occur.
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The Journal of urology · Nov 1995
Prevalence and repair of inguinal hernias in children with bladder exstrophy.
We delineated the prevalence, recurrence rates and optimal treatment of inguinal hernia in the exstrophy population. ⋯ Children with bladder exstrophy should be carefully examined for inguinal hernias before bladder closure. If a unilateral hernia is present, the contralateral side should be explored. Careful preperitoneal repair should emphasize repair of the internal ring.
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Urology is a field with many subspecialties and, as a consequence, urological research grant applications are distributed to a variety of different study sections at the National Institutes of Health (NIH). It has long been the conviction of urological investigators that urological grant funding suffers as a result of this distribution. We investigated the composition of these study sections to identify the prevalence of urological expertise (or lack thereof). The review challenges the concept that urological research grant applications are being subjected to adequate peer review. ⋯ The lack of urological expertise represented on the NIH study sections reviewing basic and clinical urological research grant applications has far reaching ramifications. Consequently, grant applications on genitourinary diseases that commonly afflict a preponderance of Americans are inadequately reviewed at the NIH. Only through the provision of appropriate peer reviewers will this problem be solved.
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The Journal of urology · Oct 1995
ReviewThe incidence and management of rectal injury associated with radical prostatectomy in a community based urology practice.
We assessed the use of combination bowel preparation before radical prostatectomy. ⋯ Combination bowel preparation permits safe closure of rectal injury at radical prostatectomy without the necessity of routine colostomy. In the event of recto-urinary fistula, conservative management is not warranted.
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The Journal of urology · Oct 1995
Comparative StudyAn outcome study of patient-controlled morphine analgesia, with or without ketorolac, following radical retropubic prostatectomy.
We compared the effects of postoperative pain control strategies on recovery after radical retropubic prostatectomy. ⋯ Pain control with ketorolac affords excellent analgesia while allowing for earlier recovery of bowel function, shorter hospitalization and lower overall costs in patients undergoing radical retropubic prostatectomy.