Nutrition reviews
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Autism spectrum disorder (ASD) is the fastest growing neurodevelopmental disorder in the United States. Besides genetic risks, environmental factors have been suggested to contribute to the increase in ASD diagnosis over the past decade. Several studies have reported abnormalities in microbiota composition and differences in microbial metabolites in children with ASD. ⋯ Here, the current evidence base regarding the gut environment and nutritional status of children with ASD is reviewed. Potential underlying mechanisms of the microbiota-gut-brain axis in ASD and the interplay between nutrition, microbiota, and ASD symptoms are also reviewed. Future studies investigating the microbiota in the context of dietary intake are needed to increase understanding of the interplay between diet and the gut microbiota in ASD and to identify potential dietary, probiotic, or prebiotic intervention strategies.
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Maintenance of fluid and electrolyte balance is essential to healthy living as dehydration and fluid overload are associated with morbidity and mortality. This review presents the current evidence for the impact of hydration status on health. The Web of Science, MEDLINE, PubMed, and Google Scholar databases were searched using relevant terms. ⋯ Fluid overload has been linked with cardiopulmonary disorders, hyponatremia, edema, gastrointestinal dysfunction, and postoperative complications. There is a growing body of evidence that links states of fluid imbalance and disease. However, in some cases, the evidence is largely associative and lacks consistency, and the number of randomized trials is limited.
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Review Meta Analysis
Effect of cheese consumption on blood lipids: a systematic review and meta-analysis of randomized controlled trials.
Cheese may affect lipids and lipoproteins differently than other high-fat dairy foods. ⋯ Despite the similar P/S ratios of hard cheese and butter, consumption of hard cheese lowers LDL-C and HDL-C when compared with consumption of butter. Whether these findings can be attributed to calcium, specific types of saturated fatty acids, or the food matrix of cheese warrants further research. .
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Energy drinks are increasingly popular among athletes and others. Advertising for these products typically features images conjuring great muscle power and endurance; however, the scientific literature provides sparse evidence for an ergogenic role of energy drinks. Although the composition of energy drinks varies, most contain caffeine; carbohydrates, amino acids, herbs, and vitamins are other typical ingredients. ⋯ In contrast, fewer studies find an ergogenic effect of energy drinks on muscle strength and power. The existing data suggest that the caffeine dose given in studies of energy drinks is insufficient to enhance neuromuscular performance. Finally, it is unclear if energy drinks are the optimal vehicle to deliver caffeine when high doses are needed to improve neuromuscular performance.
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Meta Analysis
Prevalence of overweight and obesity among children and adolescents of the Indian subcontinent: a meta-analysis.
In order to examine the prevalence of overweight and obesity in childhood within the Indian subcontinent, a meta-analysis of studies was conducted. Within the data sets analyzed, six homogeneous statistical subgroups were observed and three levels of prevalence were discernible (low, intermediate, and high). The pooled estimates of the prevalence of overweight and obesity in children were 2% (95% confidence interval [CI], 2-3%) to 6% (95% CI, 6-7%) for the low-prevalence group, 11% (95% CI, 11-12%) to 18% (95% CI, 17-18%) for the intermediate-prevalence group, and 23% (95% CI, 22-24%) to 36% (95% CI, 34-37%) for the high-prevalence group. ⋯ The intermediate group largely included urban children, whereas the high-prevalence group generally included affluent children within major urban centers. Most of the data sets reported the prevalence of overweight and obesity among children in the 10-18-year age range. The prevalence of overweight and obesity was higher among boys than girls, and had increased among urban dwellers during the last decade.