Plos One
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Evaluate response and predict prognosis of patients with newly diagnosed metastatic breast cancer treated with first line systemic therapy using European Organization for Research and Treatment of Cancer (EORTC) criteria and PET Response Criteria in solid Tumours (PERCIST). ⋯ Metabolic response evaluation with EORTC criteria and PERCIST gave similar prognostic stratification for metastatic breast cancer treated with a first line of systemic therapy.
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Under natural conditions, large seeds with physical dormancy (PY) may become water permeable earlier than small ones. However, the mechanism for this difference has not been elucidated. Thus, our aim was to evaluate the traits associated with PY in seeds of Senna multijuga (Fabaceae) and to propose a mechanism for earlier dormancy-break in large than in small seeds. ⋯ Since wet, but not dry, high temperatures break PY in sensitive seeds of S. multijuga, the data support our prediction that internal pressure potential in the seed and palisade layer thickness in the water gap (lens), which is related to seed mass (i.e. P:M ratio), act together to modulate the second step (dormancy break) of the two-stage sensitivity cycling model for PY break. In which case, large seeds are predetermined to become water-permeable earlier than small ones.
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The Cognitive Emotion Regulation Questionnaire for children (CERQ-k) is a useful clinical and research tool to identify cognitive patterns of emotion regulation that predict the presence of emotional symptomatology. This study aimed to validate the Spanish version of the CERQ-k (the CERQ-Sk) using a sample of children from Spain, which is not available. ⋯ Results suggest that the CERQ-Sk is a reliable and valid tool that can be useful for researchers and clinicians to identify maladaptive cognitive emotion regulation patterns that may increase the risk of emotional problems, and orient treatment and prevention of mental health problems in children from Spanish-speaking countries.
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The chain of survival has been shown to improve the chances of survival for victims of cardiac arrest. Post-cardiac arrest care has been demonstrated to significantly impact the survival of out-of-hospital cardiac arrest (OHCA). How post-cardiac arrest care influences the survival of OHCA patients has been a main concern in recent years. ⋯ After adjusting for covariates, neurological failure, cardiac comorbidities, hospital level, intensive care unit beds, transfer to another hospital, and length of hospital stay were independent predictors of improved survival. Cardiac rhythm on admission was a strong factor associated with survival to discharge (VF vs. non-VF: adjusted odds ratio: 3.51; 95% confidence interval: 3.06-4.01). In conclusion, cardiac comorbidities, hospital volume, cardiac rhythm on admission, transfer to another hospital and length of hospital stay had a significant positive association with survival to discharge in hospitalized OHCA patients in Taiwan.
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In this study, we analyze first whether there is a common spatial distribution of child maltreatment (CM) and intimate partner violence (IPV), and second, whether the risks of CM and IPV are influenced by the same neighborhood characteristics, and if these risks spatially overlap. To this end we used geocoded data of CM referrals (N = 588) and IPV incidents (N = 1450) in the city of Valencia (Spain). As neighborhood proxies, we used 552 census block groups. ⋯ These results show that certain neighborhood characteristics are associated with an increase in the risk of family violence, regardless of whether this violence is against children or against intimate partners. Identifying these high-risk areas can inform a more integrated community-level response to both types of family violence. Future research should consider a community-level approach to address both types of family violence, as opposed to individual-level intervention addressing each type of violence separately.