Neuroendocrinol Lett
-
Neuroendocrinol Lett · Oct 2008
Case ReportsAn alternative management for growth retarded fetus with absent end-diastolic velocity in umbilical artery and normal cardiotocography.
Intrauterine growth retardation (IUGR) is associated with fetal adverse conditions. The most important cause of growth restriction and poor perinatal outcome is chronic fetal hypoxemia (CFH). Adaptation to CFH can be studied by Doppler velocity waveform on umbilical and fetal arteries and cardiotocography (CTG). ⋯ In the case of fetal monitoring controversy assessment of umbilical blood analysis may be crucial. This examination is significant and independent of the interval between cordocentesis and the onset of CTG pathology. This interval may be utilized for intrauterine treatment and for optimizing obstetric management.
-
Neuroendocrinol Lett · Aug 2008
Cerebral function monitoring in neonates with perinatal asphyxia--preliminary results.
This study was based on foreign studies which confirmed the importance of amplitude-integrated electroencefalographic monitoring (aEEG) in the early prediction of the future neurological development of newborn infants with hypoxic syndrome. Our aim was to confirm the correlation between the type of aEEG trace and the level of brain damage in newborn infants in the early hours after the hypoxic event and to introduce this method into routine practice. ⋯ Cerebral function monitoring is a non-invasive method used for the early assessment of the severity of a hypoxic event. As it could be used in the first few hours after birth, this method could be applied to select patients suitable for therapeutic hypothermia.
-
Neuroendocrinol Lett · Aug 2008
Effect of selenium compound (selol) on the opioid activity in vincristine induced hyperalgesia.
Effect of organoselenium compound (selol), on antinociceptive action of opioid agonists in vincristine neuropathic pain model was investigated. ⋯ Therefore, concomitant administration of selenium and opioids may be beneficial in terminal neoplastic states.
-
Neuroendocrinol Lett · Apr 2008
Comparative StudyEffect of intrauterine infection and perinatal risk factors on serum concentrations of insulin like growth factor (IGF-I) in full-term and preterm newborns.
IGF-I is believed to be a key factor in fetal growth dynamics It is widely known, that serious early-onset infection in the newborn is a risk factor for further developmental disturbances in a child. However, effect of congenital infection as well as an influence of infectious and non-infectious perinatal risk factors on circulating IGF-I concentrations in newborns has not been examined, yet. ⋯ We conclude that intrauterine infection increases serum IGF-I concentration in full-term infants, but not in preterm infants, that may be a result of immaturity. We suggest serum IGF-I concentration may be considered an additional element of developmental and nutritional state assessment in infected newborn.
-
Neuroendocrinol Lett · Feb 2008
Case ReportsGraves' hyperthyroidism following primary hypothyroidism due to Hashimoto's thyroiditis in a case of thyroid hemiagenesis: case report.
Thyroid hemiagenesis (TH) is a rare inborn anomaly, resulting from failure of one thyroid lobe development. It is usually detected incidentally during investigation of concomitant thyroid disorders. The reported patient first presented hypothyroidism at the age of 49, when Hashimoto's thyroiditis (HT) and left thyroid lobe agenesis was diagnosed. ⋯ The patient, whose observation period has now reached 5 years, under LT4 replacement therapy, remains both clinically and biochemically euthyroid. The described case displays a very rare coincidence of hypothyroidism due to HT converted into Graves' hyperthyroidism, accompanying TH. Each of these three entities, may influence the thyroid function in a different way, hence, systematic follow-up and individual therapeutic management is required.