Pediatr Crit Care Me
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Pediatr Crit Care Me · Nov 2005
Case ReportsSurvival of candida sepsis in extracorporeal membrane oxygenation.
To report the survival of fungal sepsis in extracorporeal membrane oxygenation. ⋯ Candidemia, particularly Candida albicans species, may not be a contraindication for extracorporeal membrane oxygenation support. With antifungal therapy and adequate inotropic use to counter the effects of septicemia, survival can be maintained until the patient adequately recovers, allowing decannulation, removal of all catheters, and eventual bloodstream sterility.
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Pediatr Crit Care Me · Nov 2005
Comment Randomized Controlled TrialCumulative fluid intake minus output is not associated with ventilator weaning duration or extubation outcomes in children.
The effect of fluid balance on respiratory outcomes for critically ill children has not been evaluated. The only indicator of fluid balance routinely recorded across our intensive care units was estimated fluid intake and output. We sought to determine whether cumulative intake minus output (I-O) at the start of weaning predicted weaning duration and whether cumulative I-O at extubation predicted extubation failure. ⋯ Although routinely recorded, cumulative fluid I-O does not appear to have clinical utility in cases managed according to a mechanical ventilator protocol in which tidal volume and oxygenation on minimal levels of ventilator support are systematically tested.
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Pediatr Crit Care Me · Nov 2005
Clinical TrialPredictive factors for the success of noninvasive mask ventilation in infants and children with acute respiratory failure.
Noninvasive mask ventilation (NIV) is a treatment option in acute respiratory failure in adults. This study was performed to determine prognostic variables for the success of NIV in a group of infants and children with respiratory failure for a wide range of reasons. ⋯ NIV can be successfully applied to infants and children with acute respiratory failure in the setting of a pediatric intensive care unit. The level of Fio2 after 1 hr of NIV may be a predictive factor for the treatment success.
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Pediatr Crit Care Me · Nov 2005
CommentCorrelation of the Bispectral Index Monitor with the COMFORT scale in the pediatric intensive care unit.
The COMFORT scale is a commonly used observational scoring system to assess the level of sedation in ventilated children in pediatric intensive care units (PICUs). The bispectral index (BIS) monitor is a processed electroencephalographic parameter that noninvasively measures the hypnotic effect of anesthetic and sedative drugs on the brain. The objective of this study was to assess the degree of correlation between the COMFORT scale and the BIS monitor. ⋯ The BIS monitor may be a valid and useful monitor of the level of sedation of children in the PICU. We cannot expect perfect correlation between BIS values and observational scales because they measure different variables. The BIS monitor may be the best objective monitor currently available for children receiving neuromuscular blockade because it does not rely on subjective measures such as those used in the COMFORT scale. The ability of the BIS monitor to distinguish between very deep levels of sedation may be useful to prevent over-sedation of children in PICUs and to help clarify the appropriate target level of sedation for each child.
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Pediatr Crit Care Me · Nov 2005
Evaluation of tissue saturation as a noninvasive measure of mixed venous saturation in children.
Mixed venous saturation (S & OV0456;o2) is an important measurement that helps guide the care of critically ill patients. Invasive S & OV0456;o2 assessment in infants and children is often avoided because of the inherent risks. A noninvasive tissue saturation (S to 2) monitor has recently been developed that uses near-infrared spectroscopy to measure oxyhemoglobin saturation in muscle. In adult and animal studies, S to 2 correlated with oxygen delivery and S & OV0456;o2. There has been no evaluation in pediatric patients. ⋯ Noninvasive tissue saturation over the deltoid does not correlate with S & OV0456;o2 in children. It is possible that more precise probe spacing, coupled with optimal muscle-mass location, could result in more accurate measures in future investigations.