Pediatr Crit Care Me
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Pediatr Crit Care Me · Jan 2013
Factors associated with mortality in pediatric patients requiring extracorporeal life support for severe pneumonia.
In children with respiratory failure secondary to pneumonia, extracorporeal life support can be lifesaving. Our goal was to identify variables associated with mortality in children with pneumonia requiring extracorporeal life support. ⋯ In children with severe pneumonia receiving extracorporeal life support, prognostic factors associated with increased risk of death included extracorporeal life support treatment exceeding 14 days, arterial cannulation, longer duration of mechanical ventilation, and decreased ability to wean ventilator FIO2 over the first 24 hrs on extracorporeal life support. Analysis of the Extracorporeal Life Support Organization registry can identify prognostic variables, which may influence medical decision making, resource utilization, and family counseling.
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Pediatr Crit Care Me · Jan 2013
CommentCritical appraisal of Zabrocki et al: Extracorporeal membrane oxygenation for pediatric respiratory failure: survival and predictors of mortality. Crit Care Med 2011; 39:364-370.
To review the findings and discuss the implications of pediatric respiratory failure treated with extracorporeal membrane oxygenation. ⋯ This study confirms that precannulation diagnoses and variables play a role in prognosis when pediatric patients with respiratory failure are treated with extracorporeal membrane oxygenation. Results of this investigation demonstrate that survival is improving in patients without comorbidities and that patients can be mechanically ventilated for up to 14 days prior to extracorporeal support initiation before mortality is increased.
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To describe whether Berlin Heart EXCOR Pediatric pump changes in the ICU are associated with infection, hemodynamic and ventilatory instability, and neurologic injury. ⋯ Berlin Heart EXCOR Pediatric pump changes in the pediatric intensive care unit appear to be a safe procedure when conducted by a highly specialized team.
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To study the prevalence of hyperglycemia (blood glucose >126 mg/dL [>7 mmol/L]) in critically ill children older than 1 month in the first week of PICU stay and to determine its effect on mortality, organ dysfunction, and the length of PICU stay. We also determined the prevalence of glucose variability and hypoglycemia and studied their effect on mortality and morbidity. ⋯ Hyperglycemia (blood glucose >126 mg/dL [7 mmol/L]) is common in critically ill children, and values >180 mg/dL (10 mmol/L) are associated with mortality. We also noted that hyperglycemia, hypoglycemia (blood glucose <40 mg/dL [2.2 mmol/L]), and glucose variability were associated with multiple organ dysfunction.