Pediatr Crit Care Me
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Pediatr Crit Care Me · Mar 2014
Changes in Cerebral Oxygen Saturation Correlate with S100B in Infants Undergoing Cardiac Surgery With Cardiopulmonary Bypass.
The relationship of cerebral saturation measured by near-infrared spectroscopy with serum biomarker of brain injury S100B was investigated in infants undergoing cardiac surgery with cardiopulmonary bypass. ⋯ A wide cerebral arteriovenous difference measured by near-infrared spectroscopy during cardiopulmonary bypass is associated with increased serum S100B in the perioperative period and may be a modifiable risk factor for neurological injury.
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Pediatr Crit Care Me · Mar 2014
Observational StudyDetection of Alpha II-Spectrin Breakdown Products in the Serum of Neonates With Congenital Heart Disease.
To determine if alpha II-spectrin breakdown products can be detected in the serum of neonates with congenital heart disease in the perioperative period. ⋯ Spectrin breakdown products can be detected in the serum of neonates with congenital heart disease in the perioperative period and levels increased to a greater degree in infants following open-heart surgery. These findings suggest that, in future work, serum spectrin breakdown products may potentially be developed as biomarkers for brain necrosis and apoptosis in infants with congenital heart disease.