Pediatr Crit Care Me
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Pediatr Crit Care Me · Jan 2016
Observational StudyChronic Hypoxemia in Children With Congenital Heart Defect Impairs Airway Epithelial Sodium Transport.
Ambient hypoxia impairs the airway epithelial Na transport, which is crucial in lung edema reabsorption. Whether chronic systemic hypoxemia affects airway Na transport has remained largely unknown. We have therefore investigated whether chronic systemic hypoxemia in children with congenital heart defect affects airway epithelial Na transport, Na transporter-gene expression, and short-term lung edema accumulation. ⋯ The impaired airway epithelial amiloride-sensitive Na transport activity in profoundly hypoxemic children with cyanotic congenital heart defect may hinder defense against lung edema after cardiac surgery.
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Pediatr Crit Care Me · Jan 2016
Editorial CommentEnteral Nutrition in PICUs: Mission Not Impossible!
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Pediatr Crit Care Me · Jan 2016
Editorial CommentNear-Infrared Spectroscopy Oximetry: Part Science, Part Art.