Pediatr Crit Care Me
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Pediatr Crit Care Me · Dec 2019
Performance of an Automated Screening Algorithm for Early Detection of Pediatric Severe Sepsis.
To create and evaluate a continuous automated alert system embedded in the electronic health record for the detection of severe sepsis among pediatric inpatient and emergency department patients. ⋯ A continuous, automated electronic health record-based sepsis screening algorithm identified severe sepsis among children in the inpatient and emergency department settings and can be deployed to support early detection, although performance varied significantly by hospital location.
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Pediatr Crit Care Me · Dec 2019
Antithrombin Population Pharmacokinetics in Pediatric Ventricular Assist Device Patients.
Describe the pharmacokinetics of antithrombin in pediatric patients undergoing ventricular assist device therapy and provide dosing recommendations for antithrombin in this population. ⋯ Antithrombin should be dosed on fat-free mass in pediatric ventricular assist device patients. Unfractionated heparin dose and baseline antithrombin activity level should be considered when dosing antithrombin in pediatric ventricular assist device patients.