Pediatr Crit Care Me
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Pediatr Crit Care Me · Jul 2019
Etiologies and Clinical Outcomes of Patients With Secondary Hemophagocytic Lymphohistiocytosis at a Tertiary PICU.
To assess the etiologies and outcomes of patients with secondary hemophagocytic lymphohistiocytosis in the PICU. ⋯ Viral infections, particularly Epstein-Barr virus-cytomegalovirus coinfections, were a common cause of secondary hemophagocytic lymphohistiocytosis. The implication of these coinfections on the clinical course of hemophagocytic lymphohistiocytosis needs to be delineated.
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Pediatr Crit Care Me · Jul 2019
Risk Factors for Recurrent Acute Kidney Injury in Children Who Undergo Multiple Cardiac Surgeries: A Retrospective Analysis.
Determine the risk factors for repeated episodes of acute kidney injury in children who undergo multiple cardiac surgical procedures. ⋯ In a heterogeneous population of pediatric patients with congenital heart disease undergoing multiple cardiopulmonary bypass surgeries, odds of acute kidney injury after a third surgery was increased by the presence of acute kidney injury after prior procedures. Time between surgery did not play a role in increasing odds of acute kidney injury. Further studies in a larger multicenter investigation are necessary to confirm these findings.
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Pediatr Crit Care Me · Jul 2019
Risk of Severe Intraventricular Hemorrhage in the First Week of Life in Preterm Infants Transported Before 72 Hours of Age.
Evaluate the risk of severe intraventricular hemorrhage, in the first week of life, in preterm infants undergoing early interhospital transport. ⋯ Preterm infants transported in the first 72 hours of life have an increased risk of early-life severe intraventricular hemorrhage even when maternal antenatal steroids are given. The additional burden of postnatal transport could be an important component in the pathway to severe intraventricular hemorrhage. As timely in-utero transfer is not always possible, we need to focus research on improving the transport pathway to reduce this additional risk.
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Pediatr Crit Care Me · Jul 2019
Critical Illness and Cardiac Dysfunction in Anthracycline-Exposed Pediatric Oncology Patients.
To determine if the presence of cardiac dysfunction in anthracycline-exposed pediatric oncology patients is associated with an increased frequency of PICU admission or mortality. ⋯ Children with cancer who received anthracyclines, especially at higher doses, and who develop cardiac dysfunction are at higher risk of critical illness, have higher rates of multiple organ dysfunction and higher rates of mortality than anthracycline-exposed patients without cardiac dysfunction.
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Pediatr Crit Care Me · Jul 2019
Bleeding Scales Applicable to Critically Ill Children: A Systematic Review.
To summarize current bleeding scales and their validation to assess applicability to bleeding in critically ill children. ⋯ There is a lack of validated bleeding scales to adequately assess bleeding and outcomes in critically ill children. Validated scales of bleeding are necessary and urgently needed.