Pediatr Crit Care Me
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Pediatr Crit Care Me · May 2022
Observational StudyVitamin C Deficiency in Critically Ill Children: Prospective Observational Cohort Study.
To evaluate the presence of vitamin C deficiency in critically ill children admitted to the PICU. ⋯ Vitamin C deficiency was prevalent in our patients admitted to PICU.
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Pediatr Crit Care Me · May 2022
Opioid Weaning Protocol Using Morphine Compared With Nonprotocolized Methadone Associated With Decreased Dose and Duration of Opioid After Norwood Procedure.
Opioids are used to manage pain, comfort, maintain devices, and decrease oxygen consumption around Norwood palliation (NP), but in high dose and prolonged exposure, they increase risk of tolerance and iatrogenic withdrawal syndrome (IAWS). Variability in practice for IAWS prevention potentially increases opioid dose and duration. We hypothesize that protocolized weaning with morphine (MOR) versus nonprotocolized methadone (MTD) is associated with reduction in opioid exposure. ⋯ After complex NP, a protocolized opioid weaning using MOR versus MTD is associated with 65% shorter opioid duration, 10-fold decreased dose, and shortened LOS.