Pediatr Crit Care Me
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Pediatr Crit Care Me · Oct 2003
Case ReportsMagnesium sulfate for control of muscle rigidity and spasms and avoidance of mechanical ventilation in pediatric tetanus.
To describe the use of intravenous magnesium sulfate for the control of muscle spasms and severe generalized rigidity in a child with moderate to severe tetanus without the need for prolonged deep sedation, mechanical ventilation, or neuromuscular blockade. ⋯ An infusion of magnesium sulfate can be utilized to treat muscle spasms and severe generalized rigidity without the need for deep sedation, mechanical ventilation, or neuromuscular blockade. We recommend that magnesium sulfate be considered in the armamentarium of therapeutics utilized to treat muscle spasms and rigidity associated with tetanus, provided the patient's neurologic, cardiovascular, and respiratory status can be closely monitored in the pediatric intensive care unit.
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Pediatr Crit Care Me · Oct 2003
Clinical TrialResponse to volume resuscitation in children with severe malaria.
To examine whether hypovolemia is an important cause of the acidosis in children with severe malaria. ⋯ Volume depletion is present at admission in the majority of children with severe malaria complicated by acidosis. Volume expansion corrects the hemodynamic abnormalities and is associated with improved organ function and reduction in acidosis. Formal trials of volume expansion are needed to determine whether volume expansion will reduce mortality.
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Pediatr Crit Care Me · Oct 2003
Comparative StudyChanges in red blood cell integrity related to infusion pumps: a comparison of three different pump mechanisms.
To study the effects of three different infusion pumps on red blood cell (RBC) integrity. ⋯ The new pump's shuttle mechanism seems to be less injurious to RBCs compared with a conventional syringe and a peristaltic infusion pump. However, the clinical significance must be related to the hemolytic changes in the RBC units before they are transfused, which are a major source of the overall hemolytic load.