Pediatr Crit Care Me
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Pediatr Crit Care Me · Jan 2016
Randomized Controlled Trial Multicenter StudyPatterns of Sedation Weaning in Critically Ill Children Recovering From Acute Respiratory Failure.
To characterize sedation weaning patterns in typical practice settings among children recovering from critical illness. ⋯ This study characterizes sedative administration practices for pediatric patients prior to and during weaning from sedation after critical illness. It provides a novel methodology for describing weaning in an at-risk pediatric population that may be helpful in future research on weaning strategies to prevent iatrogenic withdrawal syndrome.
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Pediatr Crit Care Me · Jan 2016
ICU-Acquired Weakness Is Associated With Differences in Clinical Outcomes in Critically Ill Children.
ICU-acquired weakness, comprised critical illness myopathy and critical illness neuropathy, occurs in a significant proportion of critically ill adults and is associated with high morbidity and mortality. Little is known about ICU-acquired weakness among critically ill children. We investigated the incidence of ICU-acquired weakness among PICUs participating in the Virtual PICU Systems database. We also sought to identify associated risk factors for ICU-acquired weakness and evaluate the hypothesis that ICU-acquired weakness is associated with poor clinical outcomes. ⋯ ICU-acquired weakness is uncommonly diagnosed among PICU patients reported in Virtual PICU System. ICU-acquired weakness is associated with critical care therapies, invasive procedures, and resource utilization. Limitations of our retrospective study include underrecognition of ICU-acquired weakness and lack of standardized diagnostic criteria within Virtual PICU System. Prospective studies are needed to better understand the true incidence, risk factors, and clinical course for patients who develop ICU-acquired weakness.
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Pediatr Crit Care Me · Jan 2016
Editorial CommentMorbidity and Mortality Conference: Making It Better.