Pediatr Crit Care Me
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Pediatr Crit Care Me
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Pediatr Crit Care Me · Feb 2014
Effectiveness of a Clinical Pathway With Methadone Treatment Protocol for Treatment of Neonatal Abstinence Syndrome Following In Utero Drug Exposure to Substances of Abuse.
To evaluate the effectiveness of methadone for the treatment of neonatal abstinence syndrome when used according to a preexisting clinical pathway. ⋯ Clinical pathway for treating neonatal abstinence syndrome was closely followed at the initial diagnosis. The doses of methadone used in the first 24-48 hours of this study were insufficient for adequate symptom control. Despite a formal treatment protocol, there was substantial variability in total methadone exposure, length of treatment, and length of stay, suggesting other contributory factors for the observed variability.