Pediatr Crit Care Me
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Pediatr Crit Care Me · Jan 2014
Incidence of Catheter-Related Bloodstream Infections in Neonates Following Removal of Peripherally Inserted Central Venous Catheters.
Catheter-associated bloodstream infections are a significant source of morbidity and healthcare cost in the neonatal ICU. Previous studies examining the prevalence of bloodstream infections after removal of peripherally inserted central venous catheters in neonates are equivocal. ⋯ Although these data do not support the routine use of antibiotics for sepsis prophylaxis prior to peripherally inserted central venous catheter removal, they suggests that very low birth weight infants not recently exposed to antibiotics are at increased odds for associated adverse events following discontinuation of their peripherally inserted central venous catheter.
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Pediatr Crit Care Me · Jan 2014
CommentDoes ICU Structure Impact Patient Outcomes After Congenital Heart Surgery? A Critical Appraisal of "Care Models and Associated Outcomes in Congenital Heart Surgery" by Burstein et al (Pediatrics 2011; 127: e1482-e1489).
To review the findings and discuss the implications of different ICU care models on morbidity and mortality in pediatric patients after congenital heart surgery. ⋯ This paper suggests that the composition of the ICU is not a critical factor in determining outcomes after congenital heart surgery. Other factors, such as expertise of the nurses, physicians, and surgeons, as well as technical performance, should be considered.
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Pediatr Crit Care Me · Jan 2014
Tidal Volume Drives Inflammation During Mechanical Ventilation for Viral Respiratory Infection.
Respiratory syncytial virus lower respiratory tract infection is the most frequent cause of respiratory insufficiency necessitating mechanical ventilation in infants during the winter season. Recently, we presented a new animal model to show that mechanical ventilation aggravates respiratory syncytial virus-induced pulmonary inflammation by distinct mechanisms. We now use this model to study whether low tidal volume mechanical ventilation causes less ventilator-induced lung injury in the presence of respiratory syncytial virus lower respiratory tract infection. ⋯ Low tidal volume mechanical ventilation causes less ventilation-induced cellular and cytokine influx into the bronchoalveolar space during respiratory syncytial virus lower respiratory tract infection.
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Pediatr Crit Care Me · Jan 2014
Editorial CommentAge-specific cerebral perfusion pressure thresholds*.