Pediatr Crit Care Me
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Pediatr Crit Care Me · Nov 2013
ReviewExtracorporeal Membrane Oxygenation for Neonatal and Pediatric Respiratory Failure: An Evidence-Based Review of the Past Decade (2002-2012).
To provide a comprehensive evidence-based review of extracorporeal membrane oxygenation for neonatal and pediatric respiratory failure. ⋯ Despite a large number of published extracorporeal membrane oxygenation studies, there remains a paucity of high-quality clinical trials. The available data support continued use of extracorporeal membrane oxygenation for respiratory failure refractory to conventional therapy for neonatal and pediatric patients without significant comorbidities. Further research is needed to better quantify the benefit of extracorporeal membrane oxygenation and the utility of many therapies commonly applied to extracorporeal membrane oxygenation patients.
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Pediatr Crit Care Me · Nov 2013
Comparative Study Observational StudyOpioid Use After Cardiac Surgery in Children With Down Syndrome.
To determine the cumulative opioid doses administered to patients with Down syndrome after cardiac surgery and compare them with patients without Down syndrome. ⋯ This cohort did not provide evidence for opioid resistance in patients with Down syndrome. Younger age, longer cardiac bypass time, exposure to benzodiazepines, and neuromuscular blockade did correlate with increased opioid doses after cardiac surgery.