Pediatr Crit Care Me
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Pediatr Crit Care Me
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Pediatr Crit Care Me · Jan 2012
Comparative StudyRelationship between hyperglycemia and outcome in children with severe traumatic brain injury.
To determine the relationship between hyperglycemia and outcome in infants and children after severe traumatic brain injury. ⋯ In children with severe traumatic brain injury, hyperglycemia beyond the initial 48 hrs is associated with poor outcome. This relationship was observed in both our analysis of mean blood glucose concentrations as well as among the patients with episodic severe hyperglycemia. This observation suggests a relationship between hyperglycemia and outcome from traumatic brain injury. However, only a prospective study can answer the important question of whether manipulating serum glucose concentration can improve outcome after traumatic brain injury in children.