Pediatr Crit Care Me
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Pediatr Crit Care Me · Jan 2012
Randomized Controlled Trial Multicenter Study Comparative StudyTemperature profile and outcomes of neonates undergoing whole body hypothermia for neonatal hypoxic-ischemic encephalopathy.
Decreases below the target temperature were noted among neonates undergoing cooling in the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network Trial of whole body hypothermia for neonatal hypoxic-ischemic encephalopathy. ⋯ Term infants with a lower birth weight are at risk for decreasing temperatures of <32.0°C while undergoing body cooling using a servo-controlled system. This information suggests extra caution during the application of hypothermia as these lower birth weight infants are at risk for overcooling. Our findings may assist in planning additional trials of lower target temperature for neonatal hypoxic-ischemic encephalopathy.
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Pediatr Crit Care Me · Jan 2012
Randomized Controlled Trial Multicenter StudyIntracranial pressure and cerebral perfusion pressure responses to head elevation changes in pediatric traumatic brain injury.
To determine the effect of and dynamic interaction between head elevation on intracranial pressure and cerebral perfusion pressure in severe pediatric traumatic head injury. ⋯ In severe pediatric traumatic brain injury, the relationship between change in head of the bed and change in intracranial pressure was negative and linear. The lowest intracranial pressure was usually, but not always, achieved at highest head-of-the-bed angles. The effect size of a head-of-the-bed angle change depended, in part, on the subject's height. In contrast, cerebral perfusion pressure was mostly unaffected by head-of-the-bed changes.
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Pediatr Crit Care Me · Jan 2012
Multicenter StudyCritically ill children with pandemic influenza (H1N1) in pediatric intensive care units in Turkey.
To outline the epidemiologic features, clinical presentation, clinical courses, and outcomes in critically ill children with pandemic influenza in pediatric intensive care units. ⋯ Severe disease and high mortality rates were seen in children with pandemic influenza. Death attributable to pandemic influenza occurred in all age groups of children with or without underlying illness. Multiple organ dysfunction syndrome is associated with increased mortality, and death is frequently secondary to severe lung infection caused by pandemic influenza.
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Pediatr Crit Care Me · Jan 2012
Comparative StudyCharacterization of tracheal intubation process of care and safety outcomes in a tertiary pediatric intensive care unit.
To characterize tracheal intubation process of care and safety outcomes in a large tertiary pediatric intensive care unit using a pediatric adaptation of the National Emergency Airway Registry. Variances in process of care and safety outcome of intubation in the pediatric intensive care unit have not been described. We hypothesize that tracheal intubation is a common but high-risk procedure and that the novel pediatric adaptation of the National Emergency Airway Registry is a feasible tool to capture variances in process of care and outcomes. ⋯ Unwanted tracheal intubation-associated events occurred frequently, but severe tracheal intubation-associated events were rare. Our novel registry can be used to describe the pediatric intensive care unit tracheal intubation procedural process of care and safety outcomes.
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Pediatr Crit Care Me · Jan 2012
Comparative Study Controlled Clinical TrialInvestigation into the effect of closed-system suctioning on the frequency of pediatric ventilator-associated pneumonia in a developing country.
To investigate the effect of closed-system vs. open endotracheal suctioning on the frequency of ventilator-associated pneumonia and outcome in a pediatric intensive care unit in a developing country. ⋯ Closed-system suctioning did not affect the frequency of ventilator-associated pneumonia or patient outcome in this setting.