Pediatr Crit Care Me
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Pediatr Crit Care Me · May 2006
Octreotide efficacy in the treatment of chylothoraces following cardiac surgery in infants and children.
To examine the efficacy of octreotide in resolving chylothoraces in infants and children following cardiac surgery. ⋯ In contrast to previously published reports, we find octreotide therapy for postoperative chylothoraces to be successful in only a minority of cases.
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Pediatr Crit Care Me · Mar 2006
Comparative StudyPhysiologic implications of helium as a carrier gas for inhaled nitric oxide in a neonatal model of Bethanecol-induced bronchoconstriction.
To compare heliox to nitrogen-oxygen (nitrox) as a carrier gas for inducible nitric oxide (iNO) in the presence of pharmacologically inhaled bronchoconstriction. We hypothesized that respiratory resistance and gas exchange would improve when iNO is delivered with heliox. ⋯ The INOvent was effective for controlling heliox delivery of iNO. Despite marked reduction in respiratory resistance with heliox gas ventilation in a neonatal model of pharmacologic bronchoconstriction, nitrox might perform better as a delivery vehicle for iNO.
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Pediatr Crit Care Me · Mar 2006
Pulmonary edema in meningococcal septicemia associated with reduced epithelial chloride transport.
To test the hypothesis that meningococcal septicemia-related pulmonary edema is associated with a systemic abnormality of epithelial sodium and chloride transport and to investigate an association with hormones regulating Na transport. ⋯ We have confirmed that meningococcal septicemia-related pulmonary edema is associated with reduced systemic sodium and chloride transport. Features of reduced Cl transport were most closely associated with markers of respiratory compromise, and this was supported by the reduced chloride channel function detected on nasal potential difference measurement.