Crit Care Resusc
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Observational Study
Sepsis uncouples serum C-peptide and insulin levels in critically ill patients with type 2 diabetes mellitus.
To assess the effects of sepsis and exogenous insulin on C-peptide levels and C-peptide to insulin ratios in intensive care unit (ICU) patients with type 2 diabetes mellitus (T2DM). ⋯ C-peptide levels were elevated in critically ill patients with T2DM. In this population, sepsis increased C-peptide levels and uncoupled serum C-peptide and insulin levels. Exogenous insulin decreased both C-peptide levels and C-peptide to insulin ratios.
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Observational Study
Haemodynamic response to fluid boluses in children after cardiac surgery: a technical report.
To describe the haemodynamic response to fluid boluses (FB) in children after cardiac surgery. ⋯ In this study, the haemodynamic response to FB in children is infrequent and unsustained. Larger studies are required to demonstrate the pattern of haemodynamic response of FB in critically ill children.