Crit Care Resusc
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Two major cardiac arrest trials are evaluating different strategies that may potentially mitigate neurological injury after cardiac arrest and are allowing co-enrolment. However, one trial will target hypothermia and the other will target mild hypercapnia, in which the carbon dioxide (CO2) measurement may be influenced by the choice of temperature adjustment during arterial blood gases (ABGs) measurement. The trials have agreed to standardise assessment by the α-stat method. ⋯ Our survey findings support the acceptability of the decision to apply the α-stat approach across participating sites for both trials.
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Randomized Controlled Trial Comparative Study
Haemodynamic effects of cold versus warm fluid bolus in healthy volunteers: a randomised crossover trial.
To test the hypothesis that changes in cardiac index and mean arterial pressure (MAP) during and after a fluid bolus (FB) are altered by fluid temperature. ⋯ Intravenous FB at body temperature leads to a greater increase in cardiac index compared with room temperature, while the reverse applies to MAP. These findings imply that in healthy volunteers, when a room temperature FB is given, the temperature of the fluid rather than its volume accounts for most of the MAP increase.
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Multicenter Study Observational Study
The carbon footprint of treating patients with septic shock in the intensive care unit.
To use life cycle assessment to determine the environmental footprint of the care of patients with septic shock in the intensive care unit (ICU). ⋯ The carbon footprints of the ICUs were dominated by the energy use for heating, ventilation and air conditioning; consumables were relatively less important, with limited effect of intensity of patient care. There is large opportunity for reducing the ICUs' carbon footprint by improving the energy efficiency of buildings and increasing the use of renewable energy sources.
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Multicenter Study Observational Study
Intensive care implications of epidemic thunderstorm asthma.
To investigate the environmental precipitants, treatment and outcome of critically ill patients affected by the largest and most lethal reported epidemic of thunderstorm asthma. ⋯ Arrival of a triggering storm is associated with an increase in respirable airborne particles. Affected critically ill patients are young, have a high mortality, a short duration of bronchospasm, and a prior diagnosis of asthma is common.