Rev Neurol France
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Review Case Reports
[Recurrent Neisseria meningitidis meningitis associated with homozygote complement C7 fraction deficiency].
A 20-year old man had three episodes of meningococcal meningitis. Complement assays showed a complete deficiency of the seventh component of the complement system. This case emphasizes the need to perform complement assays in young patients with recurrent bacterial meningitis.
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Review Case Reports
[Bilateral thalamic glioma. A clinicopathological study of 2 cases].
Two cases of bilateral thalamic glioma in a 70 year-old man and a 8 year-old boy, documented by MRI and pathological data are reported. Such tumors are rare. Early symptoms may be misleading, with intellectual impairment or psychiatric disorders together with a normal CT scan. MRI and pathological findings support the view that bilateral thalamic gliomas represent a particular clinico-pathological entity among thalamic tumors.
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Review Case Reports
[Neurosarcoidosis with meningoencephalitis and tumoral granuloma].
A 24-year old woman had neurosarcoidosis with meningoencephalitis and frontal granuloma. After corticosteroid therapy for two years, CT showed that the granuloma had nearly disappeared and that there was a hydrocephalus.
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In two men presenting with muscle weakness and disturbances of equilibrium neurophysiological examination by repeated stimulations revealed responses suggestive of Lambert-Eaton syndrome. In the first month of the disease very high levels of anti-Hu antibody were found in the serum and CSF, betraying a malignant lesion. This was confirmed by autopsy 4 months later in one patient and by bronchial biopsy 16 months later in the other patient. Both had small-cell lung carcinoma associated with paraneoplastic encephalomyelitis.