Arch Ophthalmol Chic
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Arch Ophthalmol Chic · Nov 2000
Biography Historical ArticleSir Hans Sloane's contributions to ocular therapy, scientific journalism, and the creation of the British Museum.
Sir Hans Sloane, MD, (1660-1753) is best known today for his collections of books, manuscripts, and curiosities, which formed the nucleus of the British Museum at its creation the year he died. Sloane wrote about the eye from the level of knowledge of the most informed physicians of his day. He was a long-term editor of the first scientific journal published in English and was instrumental in establishing the type of scientific literature we depend on today. Arch Ophthalmol. 2000;118:1567-1573
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Arch Ophthalmol Chic · Aug 2000
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialA comparative study of topical vs retrobulbar anesthesia in complicated cataract surgery.
To evaluate and compare levels of patient discomfort and perioperative complications during phacoemulsification and implantation of a foldable intraocular lens under topical lidocaine hydrochloride and retrobulbar anesthesia in patients with cataract who also had exfoliation syndrome, uveitis, posterior synechia, phacodonesis, or previous intraocular surgery. ⋯ Surgery-related complications and patient discomfort were similar for the 2 methods of anesthesia. Topical anesthesia is justified as a means of improving safety without causing discomfort to the patient even in complicated cases of cataract surgery. Arch Ophthalmol. 2000;118:1037-1043
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To determine the location of action of apraclonidine, an alpha-adrenergic receptor agonist that reduces aqueous production and lowers intraocular pressure (IOP). ⋯ Apraclonidine's major site of pharmacologic action for reduction of aqueous production is on postjunctional alpha(2) receptors in the ciliary body. The up-regulation of alpha receptors that occurs with sympathetic denervation unmasks apraclonidine's alpha(1) effect, which clinically causes pupil dilation. Apraclonidine may be a useful medication for the diagnosis of Horner syndrome. Arch Ophthalmol. 2000;118:951-954