Arch Dermatol
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Comparative Study
Functional analyses of the stratum corneum in scars. Sequential studies after injury and comparison among keloids, hypertrophic scars, and atrophic scars.
To characterize the functional properties of the stratum corneum (SC) of various scars. ⋯ Scars, a proliferative change of the dermis, can be objectively evaluated according to functional abnormalities of the SC, because the dermis has a close relationship with the epidermis and with the SC. The functional characteristics of the SC of fresh scars and those of hypertrophic scars and keloids resemble those of retinoid-treated skin, rather than those found in epidermal hyperproliferative conditions such as psoriasis and dermatitis.
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Historical Article
The history of photography in dermatology. Milestones from the roots to the 20th century.
From the Middle Ages to the 20th century, talented artists have created illustrations of signs of human diseases. Since the birth of photography in 1840, artists and physicians have used photographic techniques to illustrate the diseases of the skin; dermatology especially relies on these visual signs. ⋯ From the early days of daguerreotypes to modern times, medical photography was developed in different stages and many physicians have taken part in the development of photographic techniques and chemistry. This historical survey describes the milestones in the development of medical photographic illustration from its beginning to the 20th century.
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To determine if intravenous high-dose "pulse" glucocorticoid therapy induced remission or reduced subsequent requirements for orally administered glucocorticoids in pemphigus vulgaris. ⋯ High-dose pulse administration of glucocorticoids is a potentially effective therapy to be considered in the treatment of patients with severe pemphigus vulgaris. Similar patients treated with conventional orally administered doses of prednisone had protracted courses requiring years of glucocorticoid therapy with no long-term remissions.