Minerva medica
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The aim of this study was to explore the correlations of inflammatory factors, caspase-cleaved cytokeratin-18 (CCCK-18), matrix metalloproteinase-9 (MMP-9) and D-Dimer (DD) with the acute physiology and chronic health evaluation (APACHE) II Score and prognosis of patients with acute cerebral hemorrhage (ACH). ⋯ ACH patients receiving emergency operation have a poorer prognosis and a higher APACHE II Score than those undergoing conservative treatment. The APACHE II Score has positive associations with the levels of inflammatory factors, CCCK-18, MMP-9 and DD. In addition, raised levels of hs-CRP, CCCK-18, MMP-9 and DD are considered as independent risk factors for poor neurologic outcomes of ACH patients.
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The newly described SARS-CoV-2 respiratory virus is now righteously presenting as an ominous threat, based on the speed with which it originated a zoonosis from bats; advancing at a similar rate, the virus has placed mankind before a pandemic, with an infection toll of some 431 million, and a lethality of 5,9 million (as of February 25, 2022). The size of the harm that this agent can unleash against us is appallingly wide, from brain ischemia to foot chilblain, passing by heart massive infarction. ⋯ This will have to be avoided, and surveillance of society on psychological terms will be one tenet. Needless to say, the role of the enteric tract in these issues is growing higher, and it will be narrated to seal the matters with the last (not the least) touch of glue.