Minerva medica
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To investigate the bactericidal effect of tea polyphenols on multidrug resistant Klebsiella pneumoniae and its antibacterial efficacy in combination with common antibiotics, and to explore its mechanism. ⋯ Tea polyphenols could be used in combination with commonly used antibiotics (imipenem, piperacillin, piperacillin/tazobactam, cefepime, cefotaxime and ceftazidime) against multidrug-resistant Klebsiella pneumoniae. It has a synergistic bactericidal effect and affects the formation of bacterial outer membrane and the production of extracellular slime-like substances (slime).
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The aim of this study is to investigate the expression and clinical value of miRNA-128 (miR-128) and insulin-like growth factor-1 (IGF-1) in patients with acute ischemic stroke (AIS). ⋯ The expression levels can reflect the severity of the disease to a certain extent and provide references for the early diagnosis and prognostic treatment in patients with acute ischemic stroke.