Minerva medica
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This study aimed to detect expression level of microRNA-383-5p (miR-383-5p) in colorectal cancer (CRC) patients following chemotherapy and its potential influence on the prognosis in CRC. ⋯ MiR-383-5p is lowly expressed in serum of CRC patients. Upregulation of miR-383-5p is beneficial to the therapeutic efficacy of neoadjuvant chemotherapy and the prognosis in CRC.
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Multicenter Study
Co-infections in critically ill adults with severe acute respiratory syndrome coronavirus 2 infection. An italian multi-centre prospective study.
To date, few studies have described Hospital-acquired infections (HAIs) during COVID-19 outbreak. To examine the incidence of HAIs in critically ill adult patients with SARS-CoV-2 infection and to observe risk factors, and the impact on outcome of HAI. ⋯ Associated factors for HAI acquisition and mortality in ICU patients were identified and cause for revision of existing infection control policies.
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The aim of this study was to screen differentially expressed microribonucleic acids (miRNAs) in the heart tissues of rats with myocardial infarction (MI), to explore the relationship between miR-30b-p and MI, and to further research the action mechanism of miR-30b-p. ⋯ MiR-30b-5p is involved in the proliferation and apoptosis of myocardial cells via regulating the Wnt/β-catenin signaling pathway, and it may become a potential target for the diagnosis of MI in clinic.