Tijdschr Diergeneesk
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Tijdschr Diergeneesk · Feb 1989
Review[Medical hemostasis. I. the treatment of hemorrhages and hemorrhagic diathesis in veterinary practice].
Bleeding patients are regularly encountered, often as an emergency, in veterinary practice. In many cases local causes will be responsible for the bleeding, but in some there will be a generalised haemostatic defect. The approach to the bleeding patient, suspected of a generalised haemostatic defect, requires a detailed history and careful physical examination in order to differentiate between hereditary and acquired haemostatic disorders and, in the case of an acquired haemostatic disorder, to detect which underlying disease caused the defect and which parts of the haemostatic system are involved. ⋯ Diagnosis, local treatment and replacement therapy with plasma or blood(products) are discussed. Drugs which are contra-indicated in bleeding patients, are also referred to. The second paper will critically evaluate the commercially available haemostatics.
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Clinical studies using a new drug for the treatment of hip dysplasia were done in approximately twenty dogs. Caniplasine was administered rather than combined treatment with phenylbutazone and a corticosteroid. The preliminary results show that this agent has a therapeutic effect. The precise mechanism of action is still obscure.