Nederlands tijdschrift voor geneeskunde
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Ned Tijdschr Geneeskd · May 2001
Review[Stereotaxic neurosurgery for treatment of Parkinson disease].
Three target structures are available in stereotactic surgery for Parkinson's disease: the thalamus, the globus pallidus and the subthalamic nucleus. The subthalamic nucleus appears to be the most promising structure. ⋯ The surgical technique of electrical stimulation causes fewer adverse effects than that of coagulation and can therefore be applied bilaterally, but does require more intense postoperative care. In the selection of patients for surgery, levodopa responsiveness plays an important role in predicting effectiveness, except in the case of tremor.