Nederlands tijdschrift voor geneeskunde
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Ned Tijdschr Geneeskd
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Ned Tijdschr Geneeskd · Feb 1996
Case Reports[Acute myopathy during treatment of status asthmaticus].
Two patients with chronic pulmonary disease, a woman of 38 and a man of 54 years old, who had developed a status asthmaticus, had difficulties being weaned from artificial ventilation. They suffered from an acute myopathy caused by a combination of high-dose corticosteroids and muscle relaxants (pancuronium, vecuronium). ⋯ The prognosis is good; almost complete recovery occurs. Muscle biopsy may reveal necrotising myopathy and occasionally, selective loss of thick myofilaments.