Acta Medica Port
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There has been an increase in the use of systematic review as a research methodology to compile and analyze large datasets of existing studies. With this increase, the recommendations to conduct this type of research also increased. ⋯ When doing a systematic review of the literature the authors become knowledgeable of the subject and, although time-consuming, they can develop a set of skills including literature research and scientific writing. A systematic review, compared to primary research, requires relatively few resources, allowing clinicians not normally involved in research to produce clinically relevant, high-quality articles.
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Observational Study
Experience of a Portuguese Center: Effectiveness of Direct-Acting Antiviral Therapy for Hepatitis C.
In late 2014, Portugal implemented a national program for the treatment of patients with chronic hepatitis C with directacting antiviral agents. This program has made Portugal one of the first European countries to implement a structured measure of treatment to eliminate this serious public health problem. The aim of this study was to assess the effectiveness of direct-acting antiviral therapy in the treatment of patients with chronic hepatitis C virus infection. ⋯ Our data showed that direct-acting antiviral-based regimens are safe and have a high success rate in the treatment of patients with hepatitis C virus infection in a real-world setting.