Ann Acad Med Singap
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Ann Acad Med Singap · Feb 2021
ReviewMetformin use in patients with type 2 diabetes mellitus and chronic kidney disease: An evidence-based review.
Practice guidelines advise caution on the use of metformin in patients with type 2 diabetes mellitus with chronic kidney disease (CKD). This review aims to examine the evidence for the benefits and risks of metformin use in patients with T2DM and CKD. ⋯ Existing recommendations to restrict metformin use in diabetes patients with CKD need to be reviewed in light of emerging evidence supporting its overall benefits in these patients.
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Ann Acad Med Singap · Feb 2021
Paediatric emergency department attendances during COVID-19 and SARS in Singapore.
We evaluated the impact of public health measures on paediatric emergency department attendances during the COVID-19 and severe acute respiratory syndrome (SARS) outbreaks in Singapore. ⋯ Nationwide public health measures in Singapore have had an impact on paediatric emergency department attendances and hospital inpatient admissions. Data from this study could inform planning and resource allocation for emergency departments in Singapore and internationally.
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Ann Acad Med Singap · Feb 2021
Epidemiology and risk stratification of minor head injuries in school-going children.
Head injuries occur commonly in children and can lead to concussion injuries. We aim to describe the epidemiology of head injuries among school-going children and identify predictors of brain concussions in Singapore. ⋯ This study provides a detailed description of the pattern of head injuries among school-going children in Singapore. High risk patients may require closer monitoring to detect post-concussion syndrome early.