Ann Acad Med Singap
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Ann Acad Med Singap · Dec 2019
Renal Transplant Outcomes in Spousal and Living-Related Donors in Malaysia.
Studies have shown that a compatible human leukocyte antigen (HLA) match can confer a favourable effect on graft outcomes. We examined the outcomes of HLA matching in renal transplant donors in Malaysia. ⋯ A good match for HLA-A, HLA-B, HLA-DR and HLA-DQ can prevent acute rejection risk in renal transplant patients. Consequently, spousal donor transplants could be a safe intervention in renal patients.
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Ann Acad Med Singap · Nov 2019
ReviewPersonalising Care in the Older Woman with Primary Breast Cancer.
The incidence of breast cancer increases with age. Despite this, most research in the field is targeted at younger patients. Age-specific guidelines are not widely referred to and guidelines which allude to the older woman as an individual are based solely on conventional factors. ⋯ This means that they are likely to have less aggressive cancers such as those who are oestrogen receptor-positive. Geriatric assessment (GA) has been used in clinical practice to identify patients that are suitable for certain treatments. More research on this group of patients' unique biological features and GA will help tailor personalised care for them.
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Ann Acad Med Singap · Nov 2019
ReviewThe Elderly Emergency Laparotomy Patient - More Than Just the Operation.
The elderly patient presenting with an acute surgical abdomen or bowel obstruction has become a common and challenging situation. These patients bring comorbidity and frailty that necessitate appropriate risk assessment and comprehensive perioperative management. ⋯ Successful management of the elderly laparotomy patient requires close coordination between surgeons, anaesthetists and physicians. The ANZELA-QI study will help establish the role of collaborative models of care and the need for perioperative care teams.