Ann Acad Med Singap
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Ann Acad Med Singap · Oct 2007
Case ReportsPeripartum acute anterior ST segment elevation myocardial infarction: an uncommon presentation of acute aortic dissection.
Atherosclerotic coronary artery thrombosis is the most common cause of acute myocardial infarction. ⋯ A high index of clinical suspicion is required in acute myocardial infarction presenting without traditional cardiovascular risk factors.
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Ann Acad Med Singap · Sep 2007
Multicenter StudyFrom a "generalist" medical graduate to a "specialty" resident: can an entry-level assessment facilitate the transition? assessing the preparedness level of new surgical trainees.
Concerns have been raised in the literature about how well the undergraduate curriculum prepares medical students for residency. An assessment was designed and administered to entering postgraduate residents in surgery to test their preparedness vis-a-vis the competence level expected of them at the beginning of their training. This paper explores the role and place of such an assessment in the medical education continuum. ⋯ This pilot study reveals definite educational gaps in both knowledge and skills among the residents studied. Such an intervention can be very informative, providing immense educational benefit to the learner, faculty and programme, and has an important place in the continuum of medical training.
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Ann Acad Med Singap · Jun 2007
Mutation screening in KCNQ1, HERG, KCNE1, KCNE2 and SCN5A genes in a long QT syndrome family.
Long QT syndrome (LQTS), an inherited cardiac arrhythmia, is a disorder of ventricular repolarisation characterised by electrocardiographic abnormalities and the onset of torsades de pointes leading to syncope and sudden death. Genetic polymorphisms in 5 well-characterised cardiac ion channel genes have been identified to be responsible for the disorder. The aim of this study is to identify disease-causing mutations in these candidate genes in a LQTS family. ⋯ We did not identify any clear identifiable genetic marker causative of LQTS, suggesting the existence of LQTS-associated genes awaiting discovery.
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Ann Acad Med Singap · Jun 2007
Comparative StudyComparison of bedside test kits for prediction of preterm delivery: phosphorylated insulin-like growth factor binding protein-1 (pIGFBP-1) test and fetal fibronectin test.
The objective of the study was to compare the effectiveness of bedside test kits for pIGFBP-1 and fetal fibronectin test in predicting preterm delivery. ⋯ Both pIGFBP-1 and fetal fibronectin tests are effective adjuvant bedside test kits for the prediction of preterm delivery in patients presenting with signs or symptoms of preterm labour. pIGFBP-1 has the higher NPV of 1.00 in predicting risk of delivery within 48 hours.
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Ann Acad Med Singap · Jun 2007
Cross-cultural adaptation and validation of Singapore Malay and Tamil versions of the EQ-5D.
The aims of this study were to cross-culturally adapt and evaluate the validity of the Singaporean Malay and Tamil versions of the EQ-5D. ⋯ In this study among primary care patients, the Singapore Malay and Tamil EQ-5D demonstrated satisfactory known-groups and convergent validity.