Ann Acad Med Singap
-
Ann Acad Med Singap · Jul 2023
Effects of sex on clinical outcomes of hypertrophic cardiomyopathy in Singapore.
Despite the growing recognition that sex can affect the presentation and outcomes in hypertrophic cardiomyopathy (HCM), this relationship is understudied in Asians. Therefore, we aimed to explore sex differences in Asian patients with HCM. ⋯ Women diagnosed with HCM were older, had more comorbidities and were more likely to develop heart failure while men had a higher risk of all-cause mortality.
-
Ann Acad Med Singap · Jul 2023
Association between genetic polymorphisms in fibrinogen genes and bleeding risk in patients treated with direct oral anticoagulants.
This study aimed to investigate the association between polymorphisms in fibrinogen genes and bleeding risk in patients receiving direct oral anticoagulants (DOACs). ⋯ To our knowledge, this is the first study to investigate the effects of polymorphisms in fibrinogen genes on DOAC response. After validation, these results will be useful for personalised DOAC therapy.
-
Natural-language artificial intelligence (AI) is a promising technological advancement poised to revolutionise the delivery of healthcare. We aim to explore the quality of ChatGPT in providing medical information regarding a common cardiology procedure-the coronary angiogram-and evaluating the potential opportunities and challenges of patient education through this natural-language AI model in the broader context. In a conversational manner, we asked ChatGPT common questions about undergoing a coronary angiogram according to the areas of: description of procedure, indications, contraindications, complications, alternatives, and follow-up. ⋯ We would expect an increasing number of patients who may choose to seek information about their health through these platforms given their accessibility and perceived reliability. Consequently, it is prudent for healthcare professionals to be cognisant of both the strengths and deficiencies of such models. While these models appear to be good adjuncts for patients to obtain information, they cannot replace the role of a healthcare provider in delivering personalised health advice and management.