Ann Acad Med Singap
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Ann Acad Med Singap · Jun 2021
Multicenter Study Observational StudyPredictors and outcomes of high-flow nasal cannula failure following extubation: A multicentre observational study.
Despite adhering to criteria for extubation, up to 20% of intensive care patients require re-intubation, even with use of post-extubation high-flow nasal cannula (HFNC). This study aims to identify independent predictors and outcomes of extubation failure in patients who failed post-extubation HFNC. ⋯ Post-extubation HFNC failure, especially in patients with stroke as a comorbidity, remains a clinical challenge and predicts poorer clinical outcomes. Our observational study highlights the need for future prospective trials to better identify patients at high risk of post-extubation HFNC failure.
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Ann Acad Med Singap · Jun 2021
Melanoma in Singapore: A 20-year review of disease and treatment outcomes.
Melanomas in Asians have different clinicopathological characteristics and prognosis from melanomas in Caucasians. This study reviewed the epidemiology and treatment outcomes of cutaneous melanoma diagnosed at a tertiary referral dermatology centre in Singapore, which has a multiracial population. The study also determined whether Asians had comparable relapse-free and overall survival periods to Caucasians in Singapore. ⋯ More physician and patient education on skin cancer awareness is needed in our Asian-predominant population for better outcomes.