Ann Acad Med Singap
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Ann Acad Med Singap
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Ann Acad Med Singap · Jun 2021
Association of APOE polymorphisms with lipid-lowering efficacy of statins in atherosclerotic cardiovascular diseases.
The apolipoprotein E (APOE) gene is a promising candidate for the diagnosis of hyperlipoproteinaemia and atherosclerosis. Polymorphisms in APOE have been reported to result in differential efficacies of statin drugs in atherosclerotic cardiovascular disease. ⋯ Polymorphism in the APOE gene is related to the efficacy of atorvastatin in reducing the serum levels of TC and LDL-C.