Arch Iran Med
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The aim of this study was to assess the current applicability of articles that show important advances in medicine. The recruited papers include those published fifty years ago in the most respected journals in the USA, England and Germany. Using PubMed Central citations since 2010, original articles closely related to papers published in 1966 in the New England Journal of Medicine (NEJM), the Lancet and the Deutsche Medizinische Wochenschrift (DMW) were identified. ⋯ The number of highly relevant articles still currently cited were determined as 12/298 (4%) in the NEJM, 11/ 628 (1.7%) in the Lancet and 1/221 (0.45%) in the DMW (0.45%). It was concluded that "halfhundred years impact index" should be regarded as a measure of 'relevance and quality over time'. Combined with impact factor, it could be a better indicator for importance of scientific journals.
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Exclusive breastfeeding (EBF) is emphasized by the World Health Organization (WHO) as the most desirable way of infant feeding in the first 6 months. EBF has beneficial health effects on mothers and infants. The aim of this study was to examine factors influencing EBF, with emphasis on household food security status and maternal mental health. ⋯ Infant gender satisfaction, economic satisfaction, unwanted pregnancy and infant birth weight were the significant factors for predicting EBF in this study. Since EBF is important for infants and mothers' health, policy-makers should devise strategies to promote and encourage EBF in the society.
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Children are among the most susceptible groups of family violence and this is an important and worrying issue all over the world. Children with disabilities are more vulnerable to family violence. Children with autism are exposed to various types of violence due to their wide range of disabilities, as well as high tensions that are imposed on their families. Family violence against children with autism has not been studied in Iran, therefore, this study was conducted to explain the concept of family violence against children with autism from the perspectives of parents in Iran. ⋯ Based on the findings of the present study from the perspective of parents, autistic children need to be cared and educated in a safe environment where they are free from any kind of violence. Their privacy and individual identities are respected, and they are provided with the required treatment and education. These conditions would maintain the dignity of such children and consequently result in appropriate behavioral outcomes. Therefore, it is suggested that a culturally sound, and stable background be provided, which when supported by professional caregivers, will ensure that the rights of autistic children are protected and emphasized.
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The genetic generalized epilepsies (GGEs) are a set of disorders presenting with generalized seizures, in addition to general spike-wave activity. The present study aims to investigate the clinical manifestations and genetic origin of generalized tonicclonic seizures and the subgroups of GGEs, including childhood absence epilepsy (CAE), juvenile absence epilepsy, and juvenile myoclonic epilepsy (JME). Information compiled from genome-wide association studies (GWASs) in the EPICure project revealed associations with many genes. ⋯ Nowadays, next-generation sequencing (NGS) approaches support neurogeneticists to unravel the predisposed putative variants in GGE to establish a better diagnosis. Consequently, previous experiments supply data for antiepileptic drugs (AEDs) to test susceptible variants, which influence the response to drugs. As a final point, all these data should provide the current GGE patients with better genetic counseling and follow-up services.